Defining a case of invasive aspergillosis by serum galactomannan

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Serum galactomannan levels in the diagnosis of invasive aspergillosis

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The incidence and mortality of invasive pulmonary aspergillosis (IPA) are rising, particularly in critically ill patients and patients with severe chronic obstructive pulmonary disease (COPD). Noninvasive aspergillosis occurring in these patients requires special attention because of the possibility of developing subsequent IPA, given the poor health and worsened immune state of these patients....

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The monitoring and prediction of treatment responses to invasive aspergillosis (IA) are difficult. We determined whether serum galactomannan index (GMI) trends early in the course of disease may be useful in predicting eventual clinical outcomes. For the subjects recruited into the multicenter Global Aspergillosis Study, serial GMIs were measured at baseline and at weeks 1, 2, and 4 following a...

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ژورنال

عنوان ژورنال: Medical Mycology

سال: 2006

ISSN: 1369-3786,1460-2709

DOI: 10.1080/13693780600835732